Dynamic Alterations of Replication Timing in Mammalian Cells
نویسندگان
چکیده
منابع مشابه
Dynamic Alterations of Replication Timing in Mammalian Cells
BACKGROUND The eukaryotic genome is divided into distinct replication timing domains, which are activated during S phase in a strictly conserved order. Cellular differentiation can alter replication timing in some loci, but recent experiments yielded conflicting data regarding the relationship between gene expression and replication timing. The genetic and epigenetic determinants of replication...
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Thank you for submitting your manuscript on mouse Rif1 and replication timing for consideration by The EMBO Journal. It has now been evaluated by three referees, whose reports are copied below. While the all consider your findings as potentially important, interesting and timely, they at the same time find the study presently still preliminary, and raise a number of very substantive concerns th...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2003
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(03)00382-8